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The Many Roads From Alternative Splicing To Cancer by grazi oliveira is a document available to read on EtoBox.
What is The Many Roads From Alternative Splicing To Cancer about?
This review discusses the role of alternative splicing in cancer, highlighting how it can lead to oncogenic variants even in the absence of driver mutations. It identifies 199 driver genes affected by aberrant splicing, detailing mechanisms for over 40 of these genes. The findings suggest that alternative splicing can activate proto-oncogenes or inactivate tumor suppressor genes, contributing to neoplastic transformation.
- Author
- grazi oliveira
- Language
- EN