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Children with congenital Zika syndrome: symptoms, comorbidities and gross motor development at 24 months of age by Lêda Maria da Costa Pinheiro Frota; Rosana Ferreira Sampaio; José Lucivan Miranda; Rita Maria Cavalcante Brasil; Ana Paula Bensemann Gontijo; Juliana Vaz de Melo Mambrini; Marina de Brito Brandão; Marisa Cotta Mancini is a Medicine article available to read on EtoBox.
What is Children with congenital Zika syndrome: symptoms, comorbidities and gross motor development at 24 months of age about?
## Background Children with congenital Zika syndrome (CZS) maintain severe motor impairments at the end of the first year of life. Presence of certain symptoms and comorbidities increase these children's vulnerability. ## Aims To evaluate gross motor function of a group of Brazilian children with CZS at 24 months of age and to investigate the association between the presence of CZS symptoms and comorbidities with gross motor development. ## Methods and procedures Fifty children with CZS participated in the study. Information was collected from medical charts, and gross motor development was evaluated by the Gross Motor Function Measure (GMFM)-88. GMFM-88 scores were compared among comorbid groups. Three subgroups of children were identified by cluster analysis, based on information from head circumference at birth, symptoms, comorbidities and gross motor function. ## Outcomes and results Significant associations (p < 0.001) were observed between number of comorbidities/symptoms and dimensions A (r = -0.57) and B (r = -0.58) of the GMFM-88. Children were grouped into 3 clusters, with different gross motor skills. Children with epilepsy and dysphagia composed the cluster with smaller
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- Author
- Lêda Maria da Costa Pinheiro Frota; Rosana Ferreira Sampaio; José Lucivan Miranda; Rita Maria Cavalcante Brasil; Ana Paula Bensemann Gontijo; Juliana Vaz de Melo Mambrini; Marina de Brito Brandão; Marisa Cotta Mancini
- Publisher
- Elsevier BV
- Published
- 2020
- Language
- EN
- Field
- Medicine (Physical Sciences)