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The diagnostic role of salivary biomarkers of oxidative stress and inflammatory status and their relationship in periodontitis stage III and grade C by Salima Senouci; Dalila Ait Yahia; Djamila Bouziane; Mahmoud Mehadj; Willy J. Malaisse is a Agricultural and Biological Sciences article available to read on EtoBox.
What is The diagnostic role of salivary biomarkers of oxidative stress and inflammatory status and their relationship in periodontitis stage III and grade C about?
Periodontitis is bacterial infection characterized by persistent inflammation, damages connective tissue and alveolar bone destruction. The present study performed to investigate that the salivary levels could be associated with progression of periodontitis so that they used as biological markers of this disease. In this study, Twenty-nine periodontitis patients were recruited from periodontology service. Control groups are consisting of twenty-eight subjects. Total antioxidant capacity (TAC), catalase activity (CAT), reduced glutathione (GSH), uric acid, malondialdehyde (MDA) and carbonyl proteins (CP), as well as inflammatory TNF-α, IL-1β, and immune IgA biomarkers were measured in saliva. Our results revealed that salivary MDA and carbonyls levels were significantly greater (P < 0.001), while TAC, GSH and uric acid were attenuated in periodontitis patients as compared to controls (P < 0.001). Moreover, high TNF-α, Il1-β and IgA levels (P < 0.001) were observed. Positive and significant correlations were noticed between probing pocket depth (PPD), clinical attachment level (CAL) and gingival index (GI) and assessed biomarkers. Whereas, negative correlations were observed between
Who reads The diagnostic role of salivary biomarkers of oxidative stress and inflammatory status and their relationship in periodontitis stage III and grade C?
It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.
- Author
- Salima Senouci; Dalila Ait Yahia; Djamila Bouziane; Mahmoud Mehadj; Willy J. Malaisse
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Agricultural and Biological Sciences (Life Sciences)