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Can I read New Guidelines to Evaluate the Response to Treatment in Solid Tumors on EtoBox?
New Guidelines to Evaluate the Response to Treatment in Solid Tumors by Patrick Therasse; Susan G. Arbuck; Elizabeth A. Eisenhauer; Jantien Wanders; Richard S. Kaplan; Larry Rubinstein; Jaap Verweij; Martine Van Glabbeke; Allan T. van Oosterom; Michaele C. Christian; Steve G. Gwyther is a Medicine article available to read on EtoBox.
What is New Guidelines to Evaluate the Response to Treatment in Solid Tumors about?
Anticancer cytotoxic agents go through a process by which their antitumor activity-on the basis of the amount of tumor shrinkage they could generate-has been investigated. In the late 1970s, the International Union Against Cancer and the World Health Organization introduced specific criteria for the codification of tumor response evaluation. In 1994, several organizations involved in clinical research combined forces to tackle the review of these criteria on the basis of the experience and knowledge acquired since then. After several years of intensive discussions, a new set of guidelines is ready that will supersede the former criteria. In parallel to this initiative, one of the participating groups developed a model by which response rates could be derived from unidimensional measurement of tumor lesions instead of the usual bidimensional approach. This new concept has been largely validated by the Response Evaluation Criteria in Solid Tumors Group and integrated into the present guidelines. This special article also provides some philosophic background to clarify the various purposes of response evaluation. It proposes a model by which a combined assessment of all existing lesio
Who reads New Guidelines to Evaluate the Response to Treatment in Solid Tumors?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Patrick Therasse; Susan G. Arbuck; Elizabeth A. Eisenhauer; Jantien Wanders; Richard S. Kaplan; Larry Rubinstein; Jaap Verweij; Martine Van Glabbeke; Allan T. van Oosterom; Michaele C. Christian; Steve G. Gwyther
- Publisher
- Oxford University Press; Oxford University Press (OUP) (ISSN 0027-8874)
- Published
- 2000
- Language
- EN
- Field
- Medicine (Health Sciences)