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Proteogenomic Insights Suggest Druggable Pathways in Endometrial Carcinoma by Yongchao Dou; Lizabeth Katsnelson; Marina A. Gritsenko; Yingwei Hu; Boris Reva; Runyu Hong; Yi-Ting Wang; Iga Kolodziejczak; Rita Jui-Hsien Lu; Chia-Feng Tsai; Wen Bu; Wenke Liu; Xiaofang Guo; Eunkyung An; Rebecca C. Arend; Jasmin Bavarva; Lijun Chen; Rosalie K. Chu; Andrzej Czekański; Teresa Davoli; Elizabeth G. Demicco; Deborah DeLair; Kelly Devereaux; Saravana M. Dhanasekaran; Peter Dottino; Bailee Dover; Thomas L. Fillmore; McKenzie Foxall; Catherine E. Hermann; Tara Hiltke; Galen Hostetter; Marcin Jędryka; Scott D. Jewell; Isabelle Johnson; Andrea G. Kahn; Amy T. Ku; Chandan Kumar-Sinha; Paweł Kurzawa; Alexander J. Lazar; Rossana Lazcano; Jonathan T. Lei; Yi Li; Yuxing Liao; Tung-Shing M. Lih; Tai-Tu Lin; John A. Martignetti; Ramya P. Masand; Rafał Matkowski; Wilson McKerrow; Mehdi Mesri; Matthew E. Monroe; Jamie Moon; Ronald J. Moore; Michael D. Nestor; Chelsea Newton; Tatiana Omelchenko; Gilbert S. Omenn; Samuel H. Payne; Vladislav A. Petyuk; Ana I. Robles; Henry Rodriguez; Kelly V. Ruggles; Dmitry Rykunov; Sara R. Savage; Athena A. Schepmoes; Tujin Shi; Zhiao Shi; Jimin Tan; Mason Taylor; Mathangi Thiagarajan; Joshua M. Wang; Karl K. Weitz; Bo Wen; C.M. Williams; Yige Wu; Matthew A. Wyczalkowski; Xinpei Yi; Xu Zhang; Rui Zhao; David Mutch; Arul M. Chinnaiyan; Richard D. Smith; Alexey I. Nesvizhskii; Pei Wang; Maciej Wiznerowicz; Li Ding; D.R. Mani; Hui Zhang; Matthew L. Anderson; Karin D. Rodland; Bing Zhang; Tao Liu; David Fenyö; Andrzej Antczak; Meenakshi Anurag; Thomas Bauer; Chet Birger; Michael J. Birrer; Melissa Borucki; Shuang Cai; Anna Calinawan; Steven A. Carr; Patricia Castro; Sandra Cerda; Daniel W. Chan; David Chesla; Marcin P. Cieslik; Sandra Cottingham; Rajiv Dhir; Marcin J. Domagalski; Brian J. Druker; Elizabeth Duffy; Nathan J. Edwards; Robert Edwards; Matthew J. Ellis; Jennifer Eschbacher; Mina Fam; Brenda Fevrier-Sullivan; Jesse Francis; John Freymann; Stacey Gabriel; Gad Getz; Michael A. Gillette; Andrew K. Godwin; Charles A. Goldthwaite; Pamela Grady; Jason Hafron; Pushpa Hariharan; Barbara Hindenach; Katherine A. Hoadley; Jasmine Huang; Michael M. Ittmann; Ashlie Johnson; Corbin D. Jones; Karen A. Ketchum; Justin Kirby; Toan Le; Avi Ma'ayan; Rashna Madan; Sailaja Mareedu; Peter B. McGarvey; Francesmary Modugno; Rebecca Montgomery; Kristen Nyce; Amanda G. Paulovich; Barbara L. Pruetz; Liqun Qi; Shannon Richey; Eric E. Schadt; Yvonne Shutack; Shilpi Singh; Michael Smith; Darlene Tansil; Ratna R. Thangudu; Matt Tobin; Ki Sung Um; Negin Vatanian; Alex Webster; George D. Wilson; Jason Wright; Kakhaber Zaalishvili; Zhen Zhang; Grace Zhao is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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d APM status can be accurately predicted using a targeted proteomic assay d MYC activity is a potential biomarker for metformin treatment d PIK3R1 in-frame indels are associated with upregulated AKT1 phosphorylation d CTNNB1 exon 3 hotspot mutations block pS45 induced bcatenin degradation

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Author

Yongchao Dou; Lizabeth Katsnelson; Marina A. Gritsenko; Yingwei Hu; Boris Reva; Runyu Hong; Yi-Ting Wang; Iga Kolodziejczak; Rita Jui-Hsien Lu; Chia-Feng Tsai; Wen Bu; Wenke Liu; Xiaofang Guo; Eunkyung An; Rebecca C. Arend; Jasmin Bavarva; Lijun Chen; Rosalie K. Chu; Andrzej Czekański; Teresa Davoli; Elizabeth G. Demicco; Deborah DeLair; Kelly Devereaux; Saravana M. Dhanasekaran; Peter Dottino; Bailee Dover; Thomas L. Fillmore; McKenzie Foxall; Catherine E. Hermann; Tara Hiltke; Galen Hostetter; Marcin Jędryka; Scott D. Jewell; Isabelle Johnson; Andrea G. Kahn; Amy T. Ku; Chandan Kumar-Sinha; Paweł Kurzawa; Alexander J. Lazar; Rossana Lazcano; Jonathan T. Lei; Yi Li; Yuxing Liao; Tung-Shing M. Lih; Tai-Tu Lin; John A. Martignetti; Ramya P. Masand; Rafał Matkowski; Wilson McKerrow; Mehdi Mesri; Matthew E. Monroe; Jamie Moon; Ronald J. Moore; Michael D. Nestor; Chelsea Newton; Tatiana Omelchenko; Gilbert S. Omenn; Samuel H. Payne; Vladislav A. Petyuk; Ana I. Robles; Henry Rodriguez; Kelly V. Ruggles; Dmitry Rykunov; Sara R. Savage; Athena A. Schepmoes; Tujin Shi; Zhiao Shi; Jimin Tan; Mason Taylor; Mathangi Thiagarajan; Joshua M. Wang; Karl K. Weitz; Bo Wen; C.M. Williams; Yige Wu; Matthew A. Wyczalkowski; Xinpei Yi; Xu Zhang; Rui Zhao; David Mutch; Arul M. Chinnaiyan; Richard D. Smith; Alexey I. Nesvizhskii; Pei Wang; Maciej Wiznerowicz; Li Ding; D.R. Mani; Hui Zhang; Matthew L. Anderson; Karin D. Rodland; Bing Zhang; Tao Liu; David Fenyö; Andrzej Antczak; Meenakshi Anurag; Thomas Bauer; Chet Birger; Michael J. Birrer; Melissa Borucki; Shuang Cai; Anna Calinawan; Steven A. Carr; Patricia Castro; Sandra Cerda; Daniel W. Chan; David Chesla; Marcin P. Cieslik; Sandra Cottingham; Rajiv Dhir; Marcin J. Domagalski; Brian J. Druker; Elizabeth Duffy; Nathan J. Edwards; Robert Edwards; Matthew J. Ellis; Jennifer Eschbacher; Mina Fam; Brenda Fevrier-Sullivan; Jesse Francis; John Freymann; Stacey Gabriel; Gad Getz; Michael A. Gillette; Andrew K. Godwin; Charles A. Goldthwaite; Pamela Grady; Jason Hafron; Pushpa Hariharan; Barbara Hindenach; Katherine A. Hoadley; Jasmine Huang; Michael M. Ittmann; Ashlie Johnson; Corbin D. Jones; Karen A. Ketchum; Justin Kirby; Toan Le; Avi Ma'ayan; Rashna Madan; Sailaja Mareedu; Peter B. McGarvey; Francesmary Modugno; Rebecca Montgomery; Kristen Nyce; Amanda G. Paulovich; Barbara L. Pruetz; Liqun Qi; Shannon Richey; Eric E. Schadt; Yvonne Shutack; Shilpi Singh; Michael Smith; Darlene Tansil; Ratna R. Thangudu; Matt Tobin; Ki Sung Um; Negin Vatanian; Alex Webster; George D. Wilson; Jason Wright; Kakhaber Zaalishvili; Zhen Zhang; Grace Zhao

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)