Can I read Diversity of Omicron sublineages and clinical characteristics in hospitalized patients in the southernmost state of Brazil on EtoBox?
Diversity of Omicron sublineages and clinical characteristics in hospitalized patients in the southernmost state of Brazil by Jaqueline Rhoden; Andressa Taíz Hoffmann; Janaína Franciele Stein; Mariana Soares da Silva; Juliana Schons Gularte; Micheli Filippi; Meriane Demoliner; Viviane Girardi; Fernando Rosado Spilki; Juliane Deise Fleck; Caroline Rigotto is a Medicine article available to read on EtoBox.
What is Diversity of Omicron sublineages and clinical characteristics in hospitalized patients in the southernmost state of Brazil about?
## Background Omicron has become the dominant variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) since first reported in November 2021. From the initially detected Wuhan lineage, sublineages BA.2, BA.4, BA.5, BQ, XAG, and XBB have emerged over time and are dominant in many countries. Therefore, the aim is to evaluate which variants are circulating and the clinical characteristics of inpatients infected with the Omicron variant. ## Methods This retrospective cohort study selected hospitalized patients admitted with respiratory symptoms to a hospital in the state of Rio Grande do Sul, Brazil, between June and July 2022. SARS-CoV-2 results were analyzed together with clinical outcomes and vaccination status. A viral genome library was prepared and forwarded to the Illumina MiSeq Platform for sequencing. ## Results In total, 37 genomes were sequenced. Concerning the Omicron sublineages, our study detected: BA.1 (21 K), BA.2 (21 L), BA.4 (22A), BA.5 (22B), BA.2.12.1 (22C), BQ.1 (22E), XBB (22F), and XAG recombinant. Omicron BA.5 (30%), BA.2 (19%), and BQ.1 (19%) were the most frequent sublineages, respectively. In total, 38% of patients present hypertension, and the
Who reads Diversity of Omicron sublineages and clinical characteristics in hospitalized patients in the southernmost state of Brazil?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Jaqueline Rhoden; Andressa Taíz Hoffmann; Janaína Franciele Stein; Mariana Soares da Silva; Juliana Schons Gularte; Micheli Filippi; Meriane Demoliner; Viviane Girardi; Fernando Rosado Spilki; Juliane Deise Fleck; Caroline Rigotto
- Publisher
- BioMed Central
- Published
- 2024
- Language
- EN
- Field
- Medicine (Health Sciences)