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This document describes the development of photoactivatable formaldehyde donors with fluorescence monitoring capabilities for biological studies. The researchers synthesized a donor called photoFAD-3 that allows controlled light-mediated release of formaldehyde while also enabling concentration monitoring via fluorescence. In vitro studies with photoFAD-3 in live cells uncovered that a concentration range of 2.2 μM formaldehyde was necessary to arrest wound healing, demonstrating the tool

Author

Nick Pino

Language

EN