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Localisation of glycans in the placenta: A comparative study of epitheliochorial, endotheliochorial, and haemomonochorial placentation by Jones, Carolyn J.P.; Dantzer, Vibeke; Leiser, Rudolf; Krebs, Christiane; Stoddart, Robert W. is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Localisation of glycans in the placenta: A comparative study of epitheliochorial, endotheliochorial, and haemomonochorial placentation about?
Specimens of mid-term (horse), near-term (pig, cow, sheep, mink) and term (human) placentae and associated tissues have been examined with a panel of 15 biotinylated lectins combined with an avidin-peroxidase revealing system. The aim of this study has been to analyse the expression of glycans at the materno-fetal interface in order to establish whether the morphological diversity exhibited by these six species is reflected by accompanying biochemical diversity, or whether similar types of glycan are expressed in tissues performing similar functions. Lectin staining intensity was scored in the following elements of the interhaemal placental barrier: maternal capillaries, maternal uterine epithelium, the materno-fetal interdigitating microvillous membrane (brush border in the human), trophoblast, and fetal capillaries. A high degree of biochemical diversity was found in the glycan expression of the various placental components within and among placental types. Each layer showed widely differing patterns of lectin binding between species, with only a few findings in common: 1) the relative lack of simple fucosyl termini, 2) the presence of non-bisected bi/tri-antennary N-glycan in mo
Who reads Localisation of glycans in the placenta: A comparative study of epitheliochorial, endotheliochorial, and haemomonochorial placentation?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Jones, Carolyn J.P.; Dantzer, Vibeke; Leiser, Rudolf; Krebs, Christiane; Stoddart, Robert W.
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1059-910X)
- Published
- 1997
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)