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Recent Advances in Systems Metabolic Engineering by Taehee Han; Alisher Nazarbekov; Xuan Zou; Sang Yup Lee is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Recent Advances in Systems Metabolic Engineering about?

Systems metabolic engineering, which integrates metabolic engineering with systems biology, synthetic biology, and evolutionary engineering, has revolutionized the sustainable production of fuels and materials through the creation of efficient microbial cell factories. Recent advancements in systems metabolic engineering targeting different biological components of the host cell have enabled the creation of highly productive microbial cell factories. This article provides a review of the recent tools and strategies used for enzyme-, genetic module-, pathway-, flux-, genome-, and cell-level engineering, supported by illustrative examples. Furthermore, we highlight recent trends in systems metabolic engineering, which involve the application of multiple tools discussed in this review. Finally, the paper addresses the challenges and perspectives of transitioning academic-level metabolic engineering studies to commercial-scale production.

Who reads Recent Advances in Systems Metabolic Engineering?

Author

Taehee Han; Alisher Nazarbekov; Xuan Zou; Sang Yup Lee

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)