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Can I read Electrophysiological and Fundoscopic Detection of Intracranial Hypertension in Craniosynostosis on EtoBox?
Electrophysiological and Fundoscopic Detection of Intracranial Hypertension in Craniosynostosis by Sohaib R. Rufai; Oliver R. Marmoy; Dorothy A. Thompson; Lara S. van de Lande; R. William Breakey; Catey Bunce; Vasiliki Panteli; Kemmy Schwiebert; Shafquet Mohamed; Frank A. Proudlock; Irene Gottlob; David J. Dunaway; Richard Hayward; Richard Bowman; Noor ul Owase Jeelani is a Medicine article available to read on EtoBox.
What is Electrophysiological and Fundoscopic Detection of Intracranial Hypertension in Craniosynostosis about?
## Abstract ## Aims To assess the diagnostic accuracy of fundoscopy and visual evoked potentials (VEPs) in detecting intracranial hypertension (IH) in patients with craniosynostosis undergoing spring-assisted posterior vault expansion (sPVE). ## Methods Children with craniosynostosis undergoing sPVE and 48-hour intracranial pressure (ICP) monitoring were included in this single-centre, retrospective, diagnostic accuracy study. Data for ICP, fundoscopy and VEPs were analysed. Primary outcome measures were papilloedema on fundoscopy, VEP assessments and IH, defined as mean ICP > 20 mmHg. Diagnostic indices were calculated for fundoscopy and VEPs against IH. Secondary outcome measures included final visual outcomes. ## Results Fundoscopic examinations were available for 35 children and isolated VEPs for 30 children, 22 of whom had at least three serial VEPs. Sensitivity was 32.1% for fundoscopy (95% confidence intervals [CI]: 15.9–52.4) and 58.3% for isolated VEPs (95% CI 36.6–77.9). Specificity for IH was 100% for fundoscopy (95% CI: 59.0–100) and 83.3% for isolated VEPs (95% CI: 35.9–99.6). Where longitudinal deterioration was suspected from some prVEPs but not corroborated by all,
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- Author
- Sohaib R. Rufai; Oliver R. Marmoy; Dorothy A. Thompson; Lara S. van de Lande; R. William Breakey; Catey Bunce; Vasiliki Panteli; Kemmy Schwiebert; Shafquet Mohamed; Frank A. Proudlock; Irene Gottlob; David J. Dunaway; Richard Hayward; Richard Bowman; Noor ul Owase Jeelani
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)