Opening book details…
Can I read Epstein-Barr virus-specific antibody response in cerebrospinal fluid and serum of patients with multiple sclerosis on EtoBox?
Epstein-Barr virus-specific antibody response in cerebrospinal fluid and serum of patients with multiple sclerosis by Massimiliano Castellazzi; Carmine Tamborino; Alice Cani; Elena Negri; Eleonora Baldi; Silva Seraceni; Maria Rosaria Tola; Enrico Granieri; Carlo Contini; Enrico Fainardi is a Medicine article available to read on EtoBox.
What is Epstein-Barr virus-specific antibody response in cerebrospinal fluid and serum of patients with multiple sclerosis about?
Cerebrospinal fluid and serum levels and intrathecal synthesis of anti-Epstein—Barr virus (EBV) IgG were measured by enzyme-linked immunosorbent assay in 80 relapsing—remitting multiple sclerosis patients grouped according to clinical and magnetic resonance imaging (MRI) evidence of disease activity. Eighty patients with other inflammatory neurological disorders (OIND) and 80 patients with non-inflammatory neurological disorders (NIND) served as neurological controls. Cerebrospinal fluid concentrations were higher in OIND than in multiple sclerosis ( p < 0.0001) and NIND ( p < 0.01) for anti-viral-capsid-antigen (anti-VCA) IgG, in multiple sclerosis than in NIND ( p < 0.01) and in OIND than in NIND ( p < 0.05) for anti-EBV nuclear antigen-1 (EBNA-1) IgG. Serum levels were more elevated in OIND than in multiple sclerosis ( p < 0.05) and in MRI inactive than in MRI active multiple sclerosis ( p < 0.0001) for anti-VCA IgG, and in multiple sclerosis than in OIND and NIND ( p < 0.01) for anti-EBNA-1 IgG. Serum titres of anti-VCA and anti-EBNA-1 IgG were also positively ( p < 0.05) and inversely ( p < 0.001) correlated, respectively, with the Expanded Disability Status Scale. An intrathe
Who reads Epstein-Barr virus-specific antibody response in cerebrospinal fluid and serum of patients with multiple sclerosis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Massimiliano Castellazzi; Carmine Tamborino; Alice Cani; Elena Negri; Eleonora Baldi; Silva Seraceni; Maria Rosaria Tola; Enrico Granieri; Carlo Contini; Enrico Fainardi
- Publisher
- SAGE Publications
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)