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Pharmacokinetics of Phosphocreatine in Myocarditis by sergejostojic is a document available to read on EtoBox.
This research developed a joint population pharmacokinetic model for phosphocreatine (PCr) and its metabolite creatine (Cr) in pediatric patients with myocarditis, utilizing data from 100 children. The study found that a four-compartment model accurately described the pharmacokinetics of both compounds, with glomerular filtration rate significantly influencing Cr clearance. The results indicated that PCr does not accumulate in vivo, while Cr concentrations increase rapidly following PCr infusion.
- Author
- sergejostojic
- Language
- EN