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Should lung transplant recipients routinely perform airway clearance techniques? A randomized trial by Prue E MUNRO; Brenda M. BUTTON; Michael BAILEY; Helen WHITFORD; Samantha J ELLIS; Gregory I. SNELL is a Medicine article available to read on EtoBox.

What is Should lung transplant recipients routinely perform airway clearance techniques? A randomized trial about?

**Background and objective:** Despite the widespread use of airway clearance (AC) techniques to clear excessive secretions and improve lung function, little is known about their efficacy following lung transplantation (LTx). This study compared the effects of two AC strategies (proactive vs reactive) on a range of clinical outcomes following LTx. **Methods:** A prospective randomized trial was conducted. Uncomplicated patients were recruited 1 month postoperatively. Patients performed AC using positive expiratory pressure either twice daily (proactive strategy) or only in the presence chest infection (reactive strategy). Lung function (FEV~1~ and FVC), CXR (Brasfield score) and bronchoscopic airway characteristics (anastomotic healing, patency and secretions) were assessed at 1, 2 and 3 months postoperatively. Adherence was measured. **Results:** Of 60 consecutive patients, 36 (18 proactive, 18 reactive) were recruited and completed the study. Both groups improved lung function (FEV~1~ 72 ± 4% to 81 ± 4%, __P__< 0.0001; FVC 69 ± 3% to 81 ± 3%, __P__< 0.0001) and Brasfield scores (17.8 ± 0.5 to 19.8 ± 0.5, __P__ < 0.002) over the study period. No significant differences for any outc

Who reads Should lung transplant recipients routinely perform airway clearance techniques? A randomized trial?

Author

Prue E MUNRO; Brenda M. BUTTON; Michael BAILEY; Helen WHITFORD; Samantha J ELLIS; Gregory I. SNELL

Publisher

Wiley

Published

2008

Language

EN

Field

Medicine (Health Sciences)