Opening book details…
Can I read Diagnostic accuracy of B-type natriuretic hormone for congenital heart disease in the first month of life on EtoBox?
Diagnostic accuracy of B-type natriuretic hormone for congenital heart disease in the first month of life by Massimiliano Cantinotti; Simona Storti; Andrea Ripoli; Luc Zyw; Maura Crocetti; Nadia Assanta; Bruno Murzi; Aldo Clerico is a Medicine article available to read on EtoBox.
What is Diagnostic accuracy of B-type natriuretic hormone for congenital heart disease in the first month of life about?
## Abstract **Background:** The goal of the present study was to evaluate the diagnostic accuracy of B-type natriuretic hormone (BNP) assay in children with congenital heart disease (CHD) in the first month of life. **Methods:** BNP was measured in 152 neonates with CHD; 154 healthy children matched for age were used as controls. BNP was measured with a fully automated platform (Triage BNP reagents, Access Immunoassay Systems, Beckman Coulter, Inc., Fullerton, CA, USA). **Results:** BNP values were significantly higher (p<0.0001) in newborns and infants with CHD compared with control (CHD patients: median 1167.5 ng/L, range 25–54,447 ng/L; healthy children: median 150.5 ng/L, range 5–866 ng/L). The diagnostic accuracy of BNP was assessed using the receiver operating characteristic (ROC) analysis, taking into account the three different groups divided according to age. Group 1: all CHD patients and healthy newborns and infants as a whole (i.e., from birth to the 30th day of life); Group 2: from the 1st to 3rd day of life; Group 3: from the 4th to 30th day of life. The area under the curve (AUC) of the ROC curve for Group 3 (0.935) was significantly higher than that for Group 1 (0.84
Who reads Diagnostic accuracy of B-type natriuretic hormone for congenital heart disease in the first month of life?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Massimiliano Cantinotti; Simona Storti; Andrea Ripoli; Luc Zyw; Maura Crocetti; Nadia Assanta; Bruno Murzi; Aldo Clerico
- Publisher
- Walter de Gruyter GmbH
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)