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Analysis of selection signatures on the Z chromosome of bidirectional selection broiler lines for the assessment of abdominal fat content by Wang, Tao (author);Zhou, Meng (author);Guo, Jing (author);Guo, Yuan-Yuan (author);Ding, Kun (author);Wang, Peng (author);Wang, Zhi-Peng (author) is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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## Background The discovery of selection signatures has enabled the identification of genomics regions under selective pressure, enhancing knowledge of evolutionary genotype-phenotypes. Sex chromosomes play an important role in species formation and evolution. Therefore, the exploration of selection signatures on sex chromosomes has important biological significance. ## Results In this study, we used the Cross Population Extend Haplotype Homozygosity Test (XPEHH), F-statistics (F~ST~) and EigenGWAS to assess selection signatures on the Z chromosome in 474 broiler chickens via Illumina chicken 60 K SNP chips. SNP genotype data were downloaded from publicly available resources. We identified 17 selection regions, amongst which 1, 11 and 12 were identified by XPEHH, F~ST~, and EigenGWAS, respectively. Each end of the Z chromosome appeared to undergo the highest levels of selection pressure. A total of 215 candidate genes were located in 17 selection regions, some of which mediated lipogenesis, fatty acid production, fat metabolism, and fat decomposition, including __FGF10, ELOVL7__, and __IL6ST__. Using abdominal adipose tissue expression data of the chickens, 187 candidate genes were

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Author
Wang, Tao (author);Zhou, Meng (author);Guo, Jing (author);Guo, Yuan-Yuan (author);Ding, Kun (author);Wang, Peng (author);Wang, Zhi-Peng (author)
Publisher
Springer Science and Business Media LLC
Published
2021
Language
EN
Field
Biochemistry, Genetics and Molecular Biology (Life Sciences)

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