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What is LC Ms Contamination about?

Chemical contamination is one of the more common problems with LC / MS. Use the highest purity chemicals available. Prioritize like this: 1. HPLC pre or trap column 2. HPLC column 3. HPLC hardware 4. Chemicals 5. ESI or APCI probe 6. Spray shield area 7. Ion Transfer Tube 8. Tube lens / Skimmer 9. Q00 / lens 0 / Q0 10. MS Dynode Generally, if 8 - 11 are dirty you will see random peaks not

Author

kamath_karthik

Language

EN