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Retrospective Analysis of 98 Cases of Maxillary Sinus Squamous Cell Carcinoma and Therapeutic Exploration by Wang, Yu; Yang, Rong; Zhao, Minghui; Guo, Wenyu; Zhang, Lun; Zhang, Wenchao; Wang, Xudong is a Medicine article available to read on EtoBox.

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## Background Maxillary sinus squamous cell carcinoma (MSSCC) is a relatively rare head and neck cancer with poorly defined prognosis, and the present study aimed to investigate the outcomes for MSSCC according to different treatments. ## Methods Tianjin Medical University Cancer Institute and Hospital pathology database was reviewed from 2007 to 2017, and 98 patients with pathologically confirmed MSSCC were enrolled. Retrospective analysis and follow-up were performed for each patient. Multivariate analysis of prognostic factors was performed using Cox’s regression model. ## Results For all the 98 cases of MSSCC, the 5-year overall survival (OS) and disease-free survival (DFS) rates were 31.0% and 29.3%, respectively. Among 98 patient, 33 patients were treated with systemic treatment (NON-SUR), 19 patients underwent neoadjuvant chemotherapy and/or radiotherapy followed by surgery (CT/RT+SUR), 38 patients received surgery followed by chemotherapy and/or radiotherapy (SUR+RT/CT), and 8 patients were performed surgery alone (SUR).The OS rate for each group was 27.3%, 57.9%, 30.6% and 37.5%, respectively, while the DFS was 21.2%, 36.8%, 31.6% and 25.0%, respectively. The OS rate of CT

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Author

Wang, Yu; Yang, Rong; Zhao, Minghui; Guo, Wenyu; Zhang, Lun; Zhang, Wenchao; Wang, Xudong

Publisher

BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2003-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1477-7819)

Published

2020

Language

EN

Field

Medicine (Health Sciences)