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What is Wnt Signaling and Colorectal Cancer Insights about?

This document discusses Wnt signaling and its relationship to colon cancer. It provides background on Wnt signaling pathways, ligands, receptors, and target genes. Mutations in Wnt pathway genes can lead to developmental defects and diseases like cancer. The APC gene is often mutated in colon cancer, inactivating APC and stabilizing beta-catenin to activate Wnt target genes involded in tumor growth. The proposed study will examine Wnt signaling relationships to colon cancer in Thai patients by collecting da

Author

t13ers

Language

EN