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Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System : Workshop Summary by Diana E. Pankevich, Miriam Davis, and Bruce M. Altevogt, rapporteurs; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Institute of Medicine of the National Academies is a nonfiction available to read on EtoBox.

What is Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System : Workshop Summary about?

Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System: Workshop Summary investigates promising current and emerging technologies, and outlines strategies to proc

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Author
Diana E. Pankevich, Miriam Davis, and Bruce M. Altevogt, rapporteurs; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Publisher
National Academies Press
Published
2011
Language
EN
ISBN
9780309212250
Category
nonfiction
Subjects
Medical, Technology, Medicine

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