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Roles of flavonoids in ischemic heart disease: Cardioprotective effects and mechanisms against myocardial ischemia and reperfusion injury by Hui Xu; Shenglong Yu; Chunxi Lin; Dingjun Dong; Jianbo Xiao; Yanbin Ye; Mingfu Wang is a Medicine article available to read on EtoBox.
What is Roles of flavonoids in ischemic heart disease: Cardioprotective effects and mechanisms against myocardial ischemia and reperfusion injury about?
Background: Flavonoids are extensively present in fruits, vegetables, grains, and medicinal plants. Myocardial ischemia and reperfusion (MI/R) comprise a sequence of detrimental incidents following myocardial ischemia. Research indicates that flavonoids have the potential to act as cardioprotective agents against MI/R injuries. Several specific flavonoids, e.g., luteolin, hesperidin, quercetin, kaempferol, and puerarin, have demonstrated cardioprotective activities in animal models. Purpose: The objective of this review is to identify the cardioprotective flavonoids, investigate their mechanisms of action, and explore their application in myocardial ischemia. Abbreviations: 12/15-LOX, 12/15-lipoxygenase; ACSL4, acyl-CoA synthetase long chain family member 4; AFB, Kaempferide-7-O-(4′′-O-acetylrhamnosyl)-3-Orutinoside; Akt, protein kinase B; ALP, alkaline phosphatase; ALT, alanine amino transferase; AMPK, AMP-activated protein kinase; Ang-1, angiotensin 1; APG, apigenin
Who reads Roles of flavonoids in ischemic heart disease: Cardioprotective effects and mechanisms against myocardial ischemia and reperfusion injury?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Hui Xu; Shenglong Yu; Chunxi Lin; Dingjun Dong; Jianbo Xiao; Yanbin Ye; Mingfu Wang
- Publisher
- Elsevier BV
- Published
- 2024
- Language
- EN
- Field
- Medicine (Life Sciences)