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Can I read Risk Factors for Mortality Before Age 18 Years in Cystic Fibrosis on EtoBox?
Risk Factors for Mortality Before Age 18 Years in Cystic Fibrosis by Susanna A. McColley; Michael S. Schechter; Wayne J. Morgan; David J. Pasta; Marcia L. Craib; Michael W. Konstan is a Medicine article available to read on EtoBox.
What is Risk Factors for Mortality Before Age 18 Years in Cystic Fibrosis about?
## Abstract ## Background Understanding early‐life risk factors for childhood death in cystic fibrosis (CF) is important for clinical care, including the identification of effective interventions. ## Methods Data from the Epidemiologic Study of Cystic Fibrosis (ESCF) collected 1994‐2005 were linked with the Cystic Fibrosis Foundation Patient Registry (CFFPR) demographic and mortality data from 2013. Inclusion criteria were ≥1 visit annually at age 3‐5 years and ≥1 FEV~1~ measurement at age 6‐8 years. Demographic data, nutritional parameters, pulmonary signs and symptoms, microbiology, and FEV~1~ were evaluated as risk factors for death before age 18 years. Multivariable Cox proportional hazards regression was used to model the simultaneous effects of risk factors associated with death before age 18 years. ## Results Among 5365 patients enrolled in ESCF who met inclusion criteria, 3880 (72%) were linked to the CFFPR. Among these, 191 (5.7%) died before age 18 years; median age at death was 13.4 ± 3.1 years. Multivariable regression showed clubbing, crackles, female sex, unknown CFTR genotype, minority race or ethnicity, Medicaid insurance (a proxy of low socioeconomic status), __Pse
Who reads Risk Factors for Mortality Before Age 18 Years in Cystic Fibrosis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Susanna A. McColley; Michael S. Schechter; Wayne J. Morgan; David J. Pasta; Marcia L. Craib; Michael W. Konstan
- Publisher
- Wiley
- Published
- 2017
- Language
- EN
- Field
- Medicine (Health Sciences)