Can I read LXR Activation Mitigates NMDA Retinal Damage on EtoBox?
LXR Activation Mitigates NMDA Retinal Damage by Daniel Jiménez is a document available to read on EtoBox.
What is LXR Activation Mitigates NMDA Retinal Damage about?
The study investigates the protective effects of liver X receptor (LXR) activation on inner retinal damage induced by N-methyl-D-aspartate (NMDA) in mice. The results show that the synthetic LXR ligand TO901317 (TO90) enhances LXRb expression, inhibits cell death, reduces apoptosis factors, and attenuates neuroinflammation, suggesting a potential therapeutic role for LXR agonists in retinal diseases related to excitotoxicity. The findings indicate that LXR activation may protect against NMDA-induced retinal
- Author
- Daniel Jiménez
- Language
- EN