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Can I read Effect of Heat and Hypoxia Stress on Mitochondrion and Energy Metabolism in the Gill of Hard Clam on EtoBox?
Effect of Heat and Hypoxia Stress on Mitochondrion and Energy Metabolism in the Gill of Hard Clam by Zhi Hu; Li Xu; Hao Song; Jie Feng; Cong Zhou; Mei-Jie Yang; Pu Shi; Yong-Ren Li; Yong-Jun Guo; Hai-Zhou Li; Tao Zhang is a Environmental Science article available to read on EtoBox.
What is Effect of Heat and Hypoxia Stress on Mitochondrion and Energy Metabolism in the Gill of Hard Clam about?
Aquatic animals suffer from heat and hypoxia stress more frequently due to global climate change and other anthropogenic activities. Heat and hypoxia stress can significantly affect mitochondrial function and energy metabolism. Here, the response and adaptation characteristics of mitochondria and energy metabolism in the gill of the hard clam Mercenaria mercenaria under heat (35 °C), hypoxia (0.2 mg/L), and heat plus hypoxia stress (35 °C, 0.2 mg/L) after 48 h exposure were investigated. Mitochondrial membrane potentials were depolarized under environmental stress. Mitochondrial fusion, fission and mitophagy played a key role in maintain mitochondrion function. The AMPK subunits showed different expression under environmental stress. Acceleration of enzyme activities (phosphofructokinase, pyruvate kinase and lactic dehydrogenase) and accumulation of anaerobic metabolites in glycolysis and TCA cycle implied that the anaerobic metabolism might play a key role in providing energy. Accumulation of amino acids might help to increase tolerance under heat and heat combined hypoxia stress. In addition, urea cycle played a key role in amino acid metabolism to prevent ammonia/nitrogen toxici
Who reads Effect of Heat and Hypoxia Stress on Mitochondrion and Energy Metabolism in the Gill of Hard Clam?
It is typically read by researchers, students, and practitioners in Environmental Science.
- Author
- Zhi Hu; Li Xu; Hao Song; Jie Feng; Cong Zhou; Mei-Jie Yang; Pu Shi; Yong-Ren Li; Yong-Jun Guo; Hai-Zhou Li; Tao Zhang
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Environmental Science (Physical Sciences)