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Composite prostheses used to repair abdominal wall defects: Physical or chemical adhesion barriers? by J. M. Bellón; N. Serrano; M. Rodríguez; N. García‐Honduvilla; G. Pascual; J. Buján is a Medicine article available to read on EtoBox.

What is Composite prostheses used to repair abdominal wall defects: Physical or chemical adhesion barriers? about?

## Abstract In a composite prosthesis, the component placed at the peritoneal interface takes the form of a physical or chemical barrier. In this experimental study performed on the white New Zealand rabbit, several composites were examined to establish the effectiveness of these barriers at impeding adhesion formation. The biomaterials tested were two polypropylene prostheses (PP) with the physical barriers of expanded polytetrafluoroethylene or polyurethane (PP + ePTFE and PP + PU) and two prostheses (one polyester and the other PP) with the absorbable chemical barriers of polyethylene glycol/glycerol and hyaluronate, respectively (PO + gl and PP + hy). The composites were used to repair 7 × 5 cm defects created in the abdominal wall of the animals by placing the implant in contact with the visceral peritoneum and the subcutaneous tissue and fixing it to recipient tissue by 4/0 polypropylene running suture. Fourteen days after surgery the animals were sacrificed and specimens were taken for light microscopy and scanning electron microscopy. Adhesions developing at the prosthesis/visceral peritoneal interface were quantified. All the prostheses induced optimal mesothelialization.

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Author
J. M. Bellón; N. Serrano; M. Rodríguez; N. García‐Honduvilla; G. Pascual; J. Buján
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1552-4973)
Published
2005
Language
EN
Field
Medicine (Health Sciences)

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