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Can I read Differentiation antigens in fetal human pancreas. Reexpression in cancer on EtoBox?

Differentiation antigens in fetal human pancreas. Reexpression in cancer by Maria Juana Escribano; Jocelyne Cordier; Marius Nap; Fiebo J. W. Ten Kate; Pierre Burtin is a Medicine article available to read on EtoBox.

What is Differentiation antigens in fetal human pancreas. Reexpression in cancer about?

An antiserum was raised against pancreatic extracts obtained from human fetuses under 5 months of gestational age. After absorption with adult tissues, this antiserum specifically recognized antigens located in the cytoplasm of fetal pancreatic acini. All of the examined pancreatic tissues, ranging from 3 t o 5 months of gestational age, showed a strong positive reaction of most of the acinar cells. The number of stained acini and the staining intensity gradually decreased from 5 months onwards and by the 7th-8th month only a few cells remained positive. Adult pancreas was completely negative as were a variety of normal adult and fetal tissues. This antiserum also reacted with tumor structures in 18/18 pancreatic adenocarcinomas as well as with pancreatic acini in the vicinity of tumor. Primary carcinomas of the liver, large bowel, stomach, breast, urinary bladder, lung and other localizations did not react with this antiserum. In some ?o whom requests for reprints should be addressed.

Who reads Differentiation antigens in fetal human pancreas. Reexpression in cancer?

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Author
Maria Juana Escribano; Jocelyne Cordier; Marius Nap; Fiebo J. W. Ten Kate; Pierre Burtin
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Test accounts (ISSN 0020-7136)
Published
1986
Language
EN
Field
Medicine (Health Sciences)

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