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Abnormal cardiovascular reflex tests are predictors of mortality in Type 2 diabetes mellitus by H. S. Chen; C. M. Hwu; B. I. Kuo; S. C. Chiang; C. F. Kwok; S. H. Lee; Y. S. Lee; M. J. Weih; L. C. Hsiao; S. H. Lin; L. T. Ho is a scholarly article available to read on EtoBox.

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**SUMMARY** **Aims** To determine whether diabetic autonomic neuropathy is an important factor contributing to mortality in Type 2 diabetes mellitus. **Methods** Between 1989 and 1993, 431 men and 181 women with Type 2 diabetes were given diabetic autonomic neuropathy cardiovascular reflex (CVR) tests. These subjects were followed for the subsequent 5–9 years to assess mortality rates. **Results** The prevalence rate of abnormal CVR tests was 46.1% in patients with the history of diabetes less than 5 years and up to 69.4% when the history of diabetes exceeded 20 years. During the follow‐up period from 1 January 1989 to 31 December 1997 (mean 7.7 years), a total of 135 participants died. The 8‐year survival rate for patients with abnormal CVR tests was 63.6% in males and 76.4% in females, compared with 80.9 and 93.3% for patients with normal CVR tests. The results were grouped as: group 1, normal CVR tests without postural hypotension (PHT); group 2, normal CVR tests with PHT; group 3, abnormal CVR tests without PHT; and group 4, abnormal CVR tests with PHT. The 8‐year survival rate was 85.4% in group 1, 80.9% in group 2, 74.5% in group 3 and 61.1% in group 4. **Conclusion** Type 2

Author

H. S. Chen; C. M. Hwu; B. I. Kuo; S. C. Chiang; C. F. Kwok; S. H. Lee; Y. S. Lee; M. J. Weih; L. C. Hsiao; S. H. Lin; L. T. Ho

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0742-3071)

Published

2001

Language

EN