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Vitamin D Levels in COVID-19 Outpatients from Western Mexico: Clinical Correlation and Effect of Its Supplementation by Sánchez-Zuno, Gabriela Athziri (author);González-Estevez, Guillermo (author);Matuz-Flores, Mónica Guadalupe (author);Macedo-Ojeda, Gabriela (author);Hernández-Bello, Jorge (author);Mora-Mora, Jesús Carlos (author);Pérez-Guerrero, Edsaúl Emilio (author);García-Chagollán, Mariel (author);Vega-Magaña, Natali (author);Turrubiates-Hernández, Francisco Javier (author);Machado-Sulbaran, Andrea Carolina (author);Muñoz-Valle, José Francisco (author) is a Medicine article available to read on EtoBox.

What is Vitamin D Levels in COVID-19 Outpatients from Western Mexico: Clinical Correlation and Effect of Its Supplementation about?

Background: The immunomodulatory effects of vitamin D are known to be beneficial in viral infections; it is also known that its deficiency is associated with a prognosis more critical of Coronavirus Disease 2019. This study aimed to determine baseline vitamin D serum concentrations and the effects of its supplementation in asymptomatic or mildly symptomatic Coronavirus Disease 2019 outpatients. Methods: 42 outpatients were included, 22 of which received a supplement of 10,000 IU of vitamin D3 for 14 days; the remaining 20 outpatients were designated as a control group. Serum levels of transferrin, ferritin, vitamin D, and D-dimer were measured at baseline in both groups. After 14 days, serum levels of total vitamin D were determined in the supplemented group. Results: At baseline, only 19% of infected outpatients had vitamin D levels corresponding to sufficiency. All outpatients with vitamin D insufficiency had at least one symptom associated with the disease, while only 75% of patients with symptoms presented sufficiency. On the seventh and fourteenth day of follow-up, the supplemented group presented fewer symptoms with respect to those non-supplemented. A vitamin D3 dose of 10,0

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Author

Sánchez-Zuno, Gabriela Athziri (author);González-Estevez, Guillermo (author);Matuz-Flores, Mónica Guadalupe (author);Macedo-Ojeda, Gabriela (author);Hernández-Bello, Jorge (author);Mora-Mora, Jesús Carlos (author);Pérez-Guerrero, Edsaúl Emilio (author);García-Chagollán, Mariel (author);Vega-Magaña, Natali (author);Turrubiates-Hernández, Francisco Javier (author);Machado-Sulbaran, Andrea Carolina (author);Muñoz-Valle, José Francisco (author)

Publisher

MDPI AG

Published

2021

Language

EN

Field

Medicine (Health Sciences)