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A Novel Porcine Dentin-derived Bone Graft Material Provides Effective Site Stability for Implant Placement After Tooth Extraction: a Randomized Controlled Clinical Trial by Lari Sapoznikov; Doron Haim; Barbara Zavan; Gérard Scortecci; Martin F. Humphrey is a Dentistry article available to read on EtoBox.

What is A Novel Porcine Dentin-derived Bone Graft Material Provides Effective Site Stability for Implant Placement After Tooth Extraction: a Randomized Controlled Clinical Trial about?

## Objectives Assessment of the clinical performance of a porcine dentin-derived particulate bone graft material for bone regeneration after tooth extraction with implant placement at 4 months, in comparison to a commercially available porcine bone-derived graft. ## Material and methods This study was a randomized, parallel-group, semi-double-blinded clinical trial evaluating the clinical safety, tolerability, and performance of Ivory Dentin GraftTM in comparison with a commercial bone-derived material in alveolar ridge preservation following tooth extraction (registered at ClinicalTrials.gov, May 12th, 2017, Identifier NCT03150472). Extraction sites were grafted with test or comparator material and a titanium implant placed at 4 months after taking a graft site biopsy. Primary endpoints were the extent of new bone growth and bone-graft integration at 4 months. ## Results The dentin graft material had statistically significantly more new bone formation (60.75% vs 42.81%, __p__ = 0.0084, __N__ = 20 vs 16), better bone-graft integration scores (good integration in 85% vs 40%, __p__ = 0.0066), and higher mean radiodensity of the bone (981.5HU vs 727.7HU, __p__ = 0.0011) at the graft s

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Author

Lari Sapoznikov; Doron Haim; Barbara Zavan; Gérard Scortecci; Martin F. Humphrey

Publisher

Springer Science and Business Media LLC

Published

2023

Language

EN

Field

Dentistry (Health Sciences)