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Duodenal ulcer perforation: A systematic literature review and narrative description of surgical techniques used to treat large duodenal defects by Darja Clinch; Dimitrios Damaskos; Fransesco Di Marzo; Salomone Di Saverio is a Medicine article available to read on EtoBox.

What is Duodenal ulcer perforation: A systematic literature review and narrative description of surgical techniques used to treat large duodenal defects about?

## BACKGROUND There is no consensus on optimal surgical treatment of large duodenal defects arising from perforated ulcers, even though such defects are challenging to repair and inadequate repair is associated with high morbidity and mortality. The aim of this study was to carry out a systematic literature review of different surgical techniques used to treat large duodenal perforations, provide a narrative description of these techniques, and propose a framework for approaching this pathology. ## METHODS PubMed/MEDLINE database was searched for articles published in English between January 1, 1970, and December 1, 2020. Studies describing surgical techniques used to treat giant duodenal ulcer perforation and their outcomes in adult patients were included. No quantitative analysis was planned because of the heterogeneity across studies. ## RESULTS Out of 960 identified records, 25 studies were eligible for inclusion. Two randomized controlled trials, one case-control trial, three cohort studies, 14 case series, and 5 case reports were included. Eight main surgical approaches are described, ranging from simple damage-control operations, such as the omental plug and triple-tube tech

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Author

Darja Clinch; Dimitrios Damaskos; Fransesco Di Marzo; Salomone Di Saverio

Publisher

Ovid Technologies (Wolters Kluwer Health)

Published

2021

Field

Medicine (Health Sciences)