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The article presents PrimeRoot, a novel genome editing technique that enables precise integration of large DNA sequences (up to 11.1 kilobases) into plant genomes, specifically demonstrated in rice. This method utilizes optimized prime editing guide RNAs and enhanced recombinases to achieve targeted insertions, significantly improving the efficiency of genetic modifications compared to traditional methods. The study successfully integrated a gene cassette that confers disease resistance in rice, showcasing

Author

delightpuppyysh

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EN