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This document discusses models of evolution used in phylogenetic analysis. It begins by introducing Markov chains as models for modeling the evolution of molecular sequences along the branches of a phylogenetic tree. It then describes the Jukes-Cantor model, which assumes equal rates of nucleotide substitution and generates sequences along a tree. The document derives the probability of observing a nucleotide after time t and the expected Jukes-Cantor distance between sequences. It concludes by discussing h

Author

Mukul Bhalla

Language

EN