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Identification and Characterization of a Murine Receptor for Galactose-terminated Glycoproteins by Wanjin Hong; Anh Van Le; Darrell Doyle is a Medicine article available to read on EtoBox.

What is Identification and Characterization of a Murine Receptor for Galactose-terminated Glycoproteins about?

The asialoglycoprotein receptor, the hepatic binding lectin for galactose-terminated glycoproteins, has been isolated and characterized from human, rabbit and rat liver. Several recent studies have shown the existence of the same receptor in murine liver. However, the biochemical structure of the receptor in murine liver has not been resolved. In this paper, we describe the identification and purification of the receptor for asialoglycoproteins from murine liver. The purified receptor has three polypeptides with apparent molecular weights of 42,000, 45,000 and 51,000, respectively, as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Furthermore, our studies suggest that the receptor from murine liver is very similar to its counterpart in rat liver, although some potential interesting differences have also been observed. Initial studies indicate that this receptor is well conserved in different mouse strains.

Who reads Identification and Characterization of a Murine Receptor for Galactose-terminated Glycoproteins?

It is typically read by researchers, students, and practitioners in Medicine.

Author
Wanjin Hong; Anh Van Le; Darrell Doyle
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Elsevier BV; Wiley; Research Square (ISSN 0270-9139)
Published
1988
Language
EN
Field
Medicine (Health Sciences)

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