Can I read Lever-press Duration as a Measure of Frustration in Sucrose and Drug Reinforcement on EtoBox?

Lever-press Duration as a Measure of Frustration in Sucrose and Drug Reinforcement by Tileena E. S. Vasquez; Ryan J. McAuley; Nikita S. Gupta; Shyny Koshy; Yorkiris Marmol-Contreras; Thomas A. Green is a scholarly article available to read on EtoBox.

What is Lever-press Duration as a Measure of Frustration in Sucrose and Drug Reinforcement about?

## Rationale: Currently there is little research into the role of frustration in substance use disorders despite research showing that frustration tolerance in humans is associated with a lower likelihood of developing substance use problems, better outcomes in recovery, and fewer relapses. ## Objective: In order to address this need, our studies use a rat model to focus on frustration-related behavior in natural reward and addiction-related behavioral procedures. frustration is defined as when a subject is unable to achieve a reinforcer, receives less of a reinforcer than anticipated, or has to work harder to achieve a reinforcer. ## Results: In these studies, bar-press durations increase when rats are in a state of frustration during self-administration of sucrose, fentanyl, or cocaine. ## Conclusions: These data also show that average bar-press durations do not correlate with the number of bar presses, meaning that press duration is an independent measurement that represents a behavioral construct distinct from craving, which is typically measured with number of bar presses. essentially, these results support that bar press durations can be used as a real-time measure of frustra

Author

Tileena E. S. Vasquez; Ryan J. McAuley; Nikita S. Gupta; Shyny Koshy; Yorkiris Marmol-Contreras; Thomas A. Green

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN