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This study investigates the correlation between PD-L1 immunoexpression and molecular alterations in histological subtypes of urothelial carcinoma (UC). Out of 26 samples, 34.61% showed a combined positive score (CPS) > 10, yet some had negative PD-L1 expression, indicating potential resistance to immune checkpoint inhibitors. The molecular analysis revealed alterations in key cancer pathways, emphasizing the need for careful evaluation of PD-L1 status in aggressive UC subtypes.

Author

Juan Daniel Prieto Cuadra

Language

EN