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The Role of Real-time Shear Wave Elastography in the Diagnosis of Idiopathic Nephrotic Syndrome and Evaluation of the Curative Effect by Yang, Xue; Hou, Fang-Lin; Zhao, Cheng; Jiang, Cai-Yun; Li, Xiu-Mei; Yu, Ning is a Medicine article available to read on EtoBox.
What is The Role of Real-time Shear Wave Elastography in the Diagnosis of Idiopathic Nephrotic Syndrome and Evaluation of the Curative Effect about?
## Purpose: To evaluate the use of real-time shear wave elastography (swe) in the assessment of renal elasticity and the efficacy of steroid treatment in adult idiopathic nephrotic syndrome (ins). ## Methods: This study included 120 patients with ins. patients were divided into steroid-sensitive and steroid-resistant groups. renal biopsy was performed. thirty healthy subjects were recruited as controls. young's modulus (ym) of the renal parenchyma was measured by swe. the ym values in each group were compared using glomerular sclerosis index (gi) and renal interstitial fibrosis (rif). ## Results: The ym values were significantly different between the ins and control groups, as well as between the steroid-sensitive and steroid-resistant groups (p < 0.05). higher ym values were associated with steroid sensitivity. the area under the receiver operating characteristic curve for the ym value in the ins group vs. control group was 0.871 (95% ci 0.815-0.927) and in the steroid-resistant group vs. control, and steroid-sensitive groups was 0.836 (95% ci 0.765-0.908). the corresponding cut-off values were 7.96 and 10.73 m/s, with 81.7% and 86.0% sensitivities, 93.3% and 77.9% specificities,
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- Author
- Yang, Xue; Hou, Fang-Lin; Zhao, Cheng; Jiang, Cai-Yun; Li, Xiu-Mei; Yu, Ning
- Publisher
- Springer-Verlag; Springer New York LLC; Springer Science and Business Media LLC (ISSN 2366-004X)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)