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Transmission of Babesia microti in Minnesota through four blood donations from the same donor over a 6‐month period by Barbara L. Herwaldt; David F. Neitzel; Jed B. Gorlin; Kathryn A. Jensen; Elizabeth H. Perry; William R. Peglow; Susan B. Slemenda; Kimberly Y. Won; Eva K. Nace; Norman J. Pieniazek; Marianna Wilson is a Medicine article available to read on EtoBox.
What is Transmission of Babesia microti in Minnesota through four blood donations from the same donor over a 6‐month period about?
**BACKGROUND** : Babesiosis is a tick‐borne zoonosis caused by intraerythrocytic protozoa. More than 40 US cases of __Babesia microti__ infection acquired by blood transfusion have been reported. This report describes the identification of a transfusion‐associated case of babesiosis and the subsequent identification of the infected blood donor and three other infected recipients of cellular blood components from three other donations by this donor. **STUDY DESIGN AND METHODS** : Serum specimens from the donors of blood that had been made into cellular components received by the index recipient and from other recipients of such components from the implicated donor were tested by the indirect fluorescent antibody (IFA) assay for antibodies to __B. microti.__ Whole blood from IFA‐positive persons was tested by PCR for __B. microti__ DNA. **RESULTS** : IFA testing of serum from 31 of 36 donors implicated a 45‐year‐old man (titer, 1 in 256), whose donation had been used for RBCs. He likely became infected when bitten by ticks while camping in Minnesota in June 1999 and had donated blood four times thereafter. As demonstrated by PCR, he remained parasitemic for at least 10 months. Of the
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- Author
- Barbara L. Herwaldt; David F. Neitzel; Jed B. Gorlin; Kathryn A. Jensen; Elizabeth H. Perry; William R. Peglow; Susan B. Slemenda; Kimberly Y. Won; Eva K. Nace; Norman J. Pieniazek; Marianna Wilson
- Publisher
- Elsevier Science; John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Elsevier; Elsevier BV; Wiley (ISSN 0372-1248)
- Published
- 2002
- Language
- EN
- Field
- Medicine (Health Sciences)