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Forensic Application of Chiral Separation of Amphetamine-type Stimulants to Impurity Analysis of Seized Methamphetamine by Capillary Electrophoresis by Yuko T. Iwata; Hiroyuki Inoue; Kenji Kuwayama; Tatsuyuki Kanamori; Kenji Tsujikawa; Hajime Miyaguchi; Tohru Kishi is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Forensic Application of Chiral Separation of Amphetamine-type Stimulants to Impurity Analysis of Seized Methamphetamine by Capillary Electrophoresis about?
The applicability of capillary electrophoresis (CE) with a UV detector using highly sulfated g-cyclodextrin as a chiral selector was examined for analysis of impurities in seized methamphetamine. Samples of methamphetamine-hydrochloride dissolved in water at a high concentration (20 mg/ mL) were analyzed. Electrokinetic injection has an advantage over hydrodynamic injection for improving the detection of trace impurities. Small peaks of the precursor impurities, such as (1R,2S)-(À)-ephedrine and (1S,2S)-(+)-pseudoephedrine, were detected and quantified without extraction. The seized drugs could be classified into three groups based on the contents of the two impurities.
Who reads Forensic Application of Chiral Separation of Amphetamine-type Stimulants to Impurity Analysis of Seized Methamphetamine by Capillary Electrophoresis?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Yuko T. Iwata; Hiroyuki Inoue; Kenji Kuwayama; Tatsuyuki Kanamori; Kenji Tsujikawa; Hajime Miyaguchi; Tohru Kishi
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0379-0738)
- Published
- 2006
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)