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This study investigates the genetic variants associated with pediatric autoimmune diseases (PADs) in children, utilizing a case-control design with genetic data from 500 patients and 500 healthy controls. Key findings indicate that variants in the HLA-DRB1, PTPN22, and CTLA-4 genes are significantly linked to conditions such as juvenile idiopathic arthritis, systemic lupus erythematosus, and type 1 diabetes. The research highlights the importance of genetic factors in disease susceptibility and the potentia

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