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P076 (0056) CLINICAL CHARACTERISTICS AND TREATMENT OUTCOME OF NODULAR LYMPHOCYTE PREDOMINANT HODGKIN‘S LYMPHOMA WITH THRLBCL-LIKE PATTERNS is a scholarly article available to read on EtoBox.

What is P076 (0056) CLINICAL CHARACTERISTICS AND TREATMENT OUTCOME OF NODULAR LYMPHOCYTE PREDOMINANT HODGKIN‘S LYMPHOMA WITH THRLBCL-LIKE PATTERNS about?

Book for the 11 th International Symposium on Hodgkin Lymphoma 30 Results: Primary endpoint of mPFS per IRF was met ; p = 0.04) (Figure 1), was consistent with mPFS per investigator (INV) (HR 0.72 [95%CI 0.57-0.91]; p = 0.006) and PFS per INV (data to be presented). mPFS events per IRF for A+AVD vs ABVD were progression (90 vs 102), death (18 vs 22), and additional therapy for noncomplete response (9 vs 22). Two-year mPFS per IRF was 82.1% (95%CI 78.8-85.0) with A+AVD vs 77.2% (95%CI 73.7-80.4) with ABVD; mPFS per INV was 81.0% (95%CI 77.6-83.9) with A+AVD vs 74.4% (95%CI 70.7-77.7] with ABVD. 28 deaths occurred in the A+AVD arm and 39 in the ABVD arm ; p = 0.20). FN occurred in 19% of A+AVD pts and 8% of ABVD pts. In A+AVD pts, G-CSF PP (n = 83) reduced FN from 21% to 11% and grade (G) ≥3 infections/infestations from 18% to 11%.

Publisher

Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins; Ovid Technologies (Wolters Kluwer Health) (ISSN 2572-9241)

Published

2018

Language

EN