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Diagnostic performance of MRI of post-laminar optic nerve invasion detection in retinoblastoma: A systematic review and meta-analysis by Se Jin Cho; Jae Hyoung Kim; Sung Hyun Baik; Leonard Sunwoo; Yun Jung Bae; Byung Se Choi is a Medicine article available to read on EtoBox.
What is Diagnostic performance of MRI of post-laminar optic nerve invasion detection in retinoblastoma: A systematic review and meta-analysis about?
Purpose Preoperative MRI detection of post-laminar optic nerve invasion (PLONI) offers guidance in assessing the probability of total tumor resection, an estimation of the extent of surgery, and screening of candidates for eye-preserving therapies or neoadjuvant chemotherapies in the patients with retinoblastoma (RB). The purpose of this systematic review and meta-analysis was to evaluate the diagnostic performance of MRI for detecting PLONI in patients with RB and to demonstrate the factors that may influence the diagnostic performance. Methods Ovid-MEDLINE and EMBASE databases were searched up to January 11, 2020, for studies identifying the diagnostic performance of MRI for detecting PLONI in patients with RB. The pooled sensitivity and specificity of all studies were calculated followed by meta-regression analysis. Results Twelve (1240 patients, 1255 enucleated globes) studies were included. The pooled sensitivity was 61%, and the pooled specificity was 88%. Higgins I 2 statistic demonstrated moderate heterogeneity in the sensitivity (I 2 = 72.23%) and specificity (I 2 = 78.11%). Spearman correlation coefficient indicated the presence of a threshold effect. In the meta-regressi
Who reads Diagnostic performance of MRI of post-laminar optic nerve invasion detection in retinoblastoma: A systematic review and meta-analysis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Se Jin Cho; Jae Hyoung Kim; Sung Hyun Baik; Leonard Sunwoo; Yun Jung Bae; Byung Se Choi
- Publisher
- Springer Science and Business Media LLC
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)