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Profile of Remimazolam in Anesthesiology: A Narrative Review of Clinical Research Progress by Wang, Mi (author);Zhao, Xian (author);Yin, Pengfei (author);Bao, Xiuxia (author);Tang, Hongli (author);Kang, Xianhui (author) is a Medicine article available to read on EtoBox.

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## Abstract Remimazolam is a novel short-acting γ-aminobutyric acid (GABA) receptor agonist with typical characteristics of benzodiazepine sedative drugs, nonorgan-dependent metabolism, long-term infusion without accumulation, and no injection pain. It is quite different from the other current sedative drugs and has broad prospects for application. It has been established that the metabolites of remimazolam are inactive, and the interactions with other drugs are weak with slight cardiopulmonary suppressive effects, showing good effectiveness and safety. During the 2-year period that it has been on the market, remimazolam has been used in multiple clinical scenarios, such as the induction and maintenance of general anesthesia and sedation in outpatient minor procedures or examinations. However, it’s use has also prompted widespread concern around the world. Therefore, given its short- and rapid-acting, controllable characteristics remimazolam deserves in-depth study in order for it to be used in fast-track surgery, comfort diagnosis and treatment. Notably, such agents might be of great significance, especially in elderly individuals, patients with critical diseases or patients with

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Author

Wang, Mi (author);Zhao, Xian (author);Yin, Pengfei (author);Bao, Xiuxia (author);Tang, Hongli (author);Kang, Xianhui (author)

Publisher

Informa UK Limited

Published

2022

Language

EN

Field

Medicine (Health Sciences)