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Can I read Pleiotropic Effects of Acetylsalicylic Acid after Coronary Artery Bypass Grafting—Beyond Platelet Inhibition on EtoBox?

Pleiotropic Effects of Acetylsalicylic Acid after Coronary Artery Bypass Grafting—Beyond Platelet Inhibition by Siwik, Dominika (author);Gajewska, Magdalena (author);Karoń, Katarzyna (author);Pluta, Kinga (author);Wondołkowski, Mateusz (author);Wilimski, Radosław (author);Szarpak, Łukasz (author);Filipiak, Krzysztof J. (author);Gąsecka, Aleksandra (author) is a Medicine article available to read on EtoBox.

What is Pleiotropic Effects of Acetylsalicylic Acid after Coronary Artery Bypass Grafting—Beyond Platelet Inhibition about?

Acetylsalicylic acid (ASA) is one of the most frequently used medications worldwide. Yet, the main indications for ASA are the atherosclerosis-based cardiovascular diseases, including coronary artery disease (CAD). Despite the increasing number of percutaneous procedures to treat CAD, coronary artery bypass grafting (CABG) remains the treatment of choice in patients with multivessel CAD and intermediate or high anatomical lesion complexity. Taking into account that CABG is a potent activator of inflammation, ASA is an important part in the postoperative therapy, not only due to ASA antiplatelet action, but also as an anti-inflammatory agent. Additional benefits of ASA after CABG include anticancerogenic, hypotensive, antiproliferative, anti-osteoporotic, and neuroprotective effects, which are especially important in patients after CABG, prone to hypertension, graft occlusion, atherosclerosis progression, and cognitive impairment. Here, we discuss the pleiotropic effects of ASA after CABG and provide insights into the mechanisms underlying the benefits of treatment with ASA, beyond platelet inhibition. Since some of ASA pleiotropic effects seem to increase the risk of bleeding, it c

Who reads Pleiotropic Effects of Acetylsalicylic Acid after Coronary Artery Bypass Grafting—Beyond Platelet Inhibition?

It is typically read by researchers, students, and practitioners in Medicine.

Author
Siwik, Dominika (author);Gajewska, Magdalena (author);Karoń, Katarzyna (author);Pluta, Kinga (author);Wondołkowski, Mateusz (author);Wilimski, Radosław (author);Szarpak, Łukasz (author);Filipiak, Krzysztof J. (author);Gąsecka, Aleksandra (author)
Publisher
MDPI AG
Published
2021
Language
EN
Field
Medicine (Health Sciences)

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