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Predicting DNA G-Quadruplex Topologies by varshaadm2020 is a document available to read on EtoBox.
What is Predicting DNA G-Quadruplex Topologies about?
The document introduces G4ShapePredictor (G4SP), a machine learning application designed to predict the folding topology of DNA G-quadruplexes (G4s) based on their nucleic acid sequences. G4s are crucial in biological processes and can adopt various topologies, which are essential for understanding their interactions with drugs. The application uses a dataset of 1005 sequence-topology pairs and incorporates a threshold optimization strategy to enhance prediction accuracy, achieving an average multi-class cl
- Author
- varshaadm2020
- Language
- EN