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What is Tumor Lysis Syndrome in Pediatrics about?

Tumor lysis syndrome is a metabolic disturbance characterized by hyperuricemia, hyperphosphatemia, hyperkalemia, and hypocalcemia, often leading to acute renal failure in patients with lymphoproliferative malignancies. The severity of these metabolic changes is influenced by factors such as chemotherapy timing, cell lysis magnitude, and patient hydration status. This review discusses the pathogenesis, risk factors, and management strategies for tumor lysis syndrome, emphasizing the importance of monitoring

Author

Pablo Saborio Chacon

Language

EN