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Successful Treatment of Distal Coronary Guidewire-induced Perforation with Balloon Catheter Delivery of Intracoronary Thrombin by Tim A. Fischell; Elie H. Korban; Michael A. Lauer is a Medicine article available to read on EtoBox.

What is Successful Treatment of Distal Coronary Guidewire-induced Perforation with Balloon Catheter Delivery of Intracoronary Thrombin about?

Distal coronary artery perforation with a coronary guidewire is a relatively rare but potentially fatal complication during PTCA. Historically, these types of perforations have been easy to control with reversal of heparin anticoagulation combined with prolonged distal balloon inflation. In the modern era, with widespread use of potent glycoprotein IIb/IIIa inhibitors, this type of distal wire perforation has become more difficult to manage and potentially lethal. In this article, we report two cases of guidewire-related distal coronary artery perforation, successfully treated using a new technique using localized, distal intracoronary thrombin injection. During prolonged low-pressure balloon inflation, a small dose of thrombin was injected just proximal to the wire perforation site via the lumen of a coronary balloon catheter. This approach appears to be a relatively rapid and effective way to control this troublesome complication.

Who reads Successful Treatment of Distal Coronary Guidewire-induced Perforation with Balloon Catheter Delivery of Intracoronary Thrombin?

Author

Tim A. Fischell; Elie H. Korban; Michael A. Lauer

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1522-1946)

Published

2003

Language

EN

Field

Medicine (Health Sciences)