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Thoracoabdominal Asynchrony and Ratio of Time to Peak Tidal Expiratory Flow Over Total Expiratory Time in Adolescents with Cystic Fibrosis by Janice M. Hunter; Elizabeth E. Sperry; Sophie Ravilly; Andrew A. Colin is a Medicine article available to read on EtoBox.
What is Thoracoabdominal Asynchrony and Ratio of Time to Peak Tidal Expiratory Flow Over Total Expiratory Time in Adolescents with Cystic Fibrosis about?
Thoracoabdominal asynchrony (TAA) and the ratio of time to peak tidal expiratory flow over total expiratory time (T ME /T E ) have been used to assess airway obstruction in infants and adults. We obtained these measurements using calibrated respiratory inductance plethysmography (RIP) on 15 adolescents and young adults with cystic fibrosis (CF) and varying disease severity. The measurements were then compared to 15 normal age-matched controls. TAA was expressed as a phase angle () calculated from the abdominal (AB) and ribcage (RC) signals acquired from scalar strip chart recordings. Using CODAS (DATAQ Instruments, Akron, OH) software, the analog signals were digitized, and the differentiated sum (AB + RC) signal was used to calculate T ME /T E . Forced vital capacity (FVC) and forced expiratory volume in 1 sec (FEV 1 ) were obtained using RIP in all subjects. Subjects with CF had a significantly higher mean than the control subjects (15°vs. 8°, respectively, P = 0.01). In the CF patients the specificity of a high as an indicator of abnormality was 80%, while the sensitivity was 65%. There was no correlation in the magnitude of and disease severity as assessed by FVC or FEV 1 . The
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- Author
- Janice M. Hunter; Elizabeth E. Sperry; Sophie Ravilly; Andrew A. Colin
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 8755-6863)
- Published
- 1999
- Language
- EN
- Field
- Medicine (Health Sciences)