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Can I read Synthesis Of New 5-aminoorotic Acid Derivatives As Antimicrobial Agents on EtoBox?

Synthesis Of New 5-aminoorotic Acid Derivatives As Antimicrobial Agents by Meriem EL KOLLI; Abdallah MAHAMOUD; Adama COULIBALY; Jacqueline CHEVALIER; Andre CREMIEUX; Jacques BARBE is a Chemistry article available to read on EtoBox.

What is Synthesis Of New 5-aminoorotic Acid Derivatives As Antimicrobial Agents about?

Reaction between 5-Aminoorotic acid and alky] or aryl halides in dimethylformamide gave esters and/or 1-alkyl substituted orotates depending upon experimental conditions. These compounds were converted into the corresponding 5-acylamino derivatives. The later derivatives were tested in vitro against gram+ and gram-bacteria. The great majority of them show significant growth inhibitory effects. Moreover, some others are specific inhibitors for gram+ bacteria.

Who reads Synthesis Of New 5-aminoorotic Acid Derivatives As Antimicrobial Agents?

It is typically read by researchers, students, and practitioners in Chemistry.

Author
Meriem EL KOLLI; Abdallah MAHAMOUD; Adama COULIBALY; Jacqueline CHEVALIER; Andre CREMIEUX; Jacques BARBE
Published
1996
Language
EN
Field
Chemistry (Physical Sciences)

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