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This document summarizes a study on minocycline block copolymer micelles and their anti-inflammatory effects. The study encapsulated minocycline (MH), an antibiotic with neuroprotective properties, into polyion complex micelles using a calcium-MH chelate and copolymer. Light scattering and NMR confirmed micelle formation with a radius of ~100 nm incorporating ~50% MH. The micelles sustained MH release for 24 hours and protected it from degradation. They were non-toxic, reduced inflammation in microglia acti

Author

Verónica Romero

Language

EN