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Stevens-Johnson syndrome (SJS) is a severe, immune-mediated hypersensitivity reaction often triggered by medications, characterized by keratinocyte necrosis and epidermal detachment. It presents with flu-like symptoms followed by painful skin lesions and mucosal erosions, requiring immediate medical attention and supportive care. Management includes withdrawal of the causative agent, monitoring for infections, and addressing complications, with a mortality rate of approximately 10% for SJS and 30% for toxic

Author

leksione7

Language

EN