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What is A Pilot Randomized Trial of Oral Magnesium Supplementation on Supraventricular Arrhythmias about?

Mg & AF Pilot MS 1 Corresponding author: Pamela Lutsey, PhD. Division of Epidemiology and Community Health, School of Public Health, University of Minnesota. 1300 S 2nd St, 300 West Bank Office Building, Minneapolis, MN 55454. Email: [email protected]. Phone: +1 612-624-5812 1 Abstract 2 Background: Magnesium is believed to have a physiologic role in cardiac contractility, and evidence from epidemiologic and clinical studies has suggested that low serum concentrations of magnesium may be associated with increased risk of atrial fibril... 2 Objective: As part of the planning effort for a large randomized trial to prevent AF with magnesium supplementation, we conducted a 12-week pilot study to assess adherence to oral magnesium supplementation and matching placebo, estimate the effect on... 2 Design: Double-blind randomized pilot clinical trial comparing supplementation with 400 mg magnesium oxide daily (versus placebo) over 12 weeks of follow-up. The ZioPatch was applied for 14 days at baseline and the end of follow-up. Adherence to the... 2 Results: A total of 59 participants, 73% women and average age 62 years, were randomized. 98% of participants completed follow-up. Those assig

Author

Pamela L Lutsey

Language

EN